thermoregulation, mathematical model, computer simulation, cooling garment, cooling control, vasoconstriction


Current state-of-the-art thermoregulatory models do not predict body temperatures with the accuracies that are required for the development of automatic cooling control in liquid cooling garment (LCG) systems. Automatic cooling control would be beneficial in a variety of space, aviation, military, and industrial environments for optimizing cooling efficiency, for making LCGs as portable and practical as possible, for alleviating the individual from manual cooling control, and for improving thermal comfort and cognitive performance. In this study, we adopt the Fiala thermoregulatory model, which has previously demonstrated state-of-the-art predictive abilities in air environments, for use in LCG environments. We validate the numerical formulation with analytical solutions to the bioheat equation, and find our model to be accurate and stable with a variety of different grid configurations. We then compare the thermoregulatory model s tissue temperature predictions with experimental data where individuals, equipped with an LCG, exercise according to a 700 W rectangular type activity schedule. The root mean square (RMS) deviation between the model response and the mean experimental group response is 0.16°C for the rectal temperature and 0.70°C for the mean skin temperature, which is within state-of-the-art variations. However, with a mean absolute body heat storage error (e_BHS_mean) of 9.7 W·h, the model fails to satisfy the ±6.5 W·h accuracy that is required for the automatic LCG cooling control development. In order to improve model predictions, we modify the blood flow dynamics of the thermoregulatory model. Instead of using step responses to changing requirements, we introduce exponential responses to the muscle blood flow and the vasoconstriction command. We find that such modifications have an insignificant effect on temperature predictions. However, a new vasoconstriction dependency, i.e. the rate of change of hypothalamus temperature weighted by the hypothalamus error signal (DThy·dThy/dt), proves to be an important signal that governs the thermoregulatory response during conditions of simultaneously increasing core and decreasing skin temperatures, which is a common scenario in LCG environments. With the new DThy·dThy/dt dependency in the vasoconstriction command, the e_BHS_mean for the exercise period is reduced by 59% (from 12.9 W·h to 5.2 W·h). Even though the new e_BHS_mean of 5.8 W·h for the total activity schedule is within the target accuracy of ±6.5 W·h, e_BHS fails to stay within the target accuracy during the entire activity schedule. With additional improvements to the central blood pool formulation, the LCG boundary condition, and the agreement between model set-points and actual experimental initial conditions, it seems possible to achieve the strict accuracy that is needed for automatic cooling control development.


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Graduation Date



Kapat, Jayanta


Doctor of Philosophy (Ph.D.)


College of Engineering and Computer Science


Mechanical, Materials and Aerospace Engineering

Degree Program

Mechanical Engineering








Release Date

December 2008

Length of Campus-only Access


Access Status

Doctoral Dissertation (Open Access)