Keywords

Friedreich's ataxia, acoustic analysis, phonatory, sustained vowel, voice, spectral analyses, adsv

Abstract

This study employed spectral analyses for acoustic measures of sustained vowel productions from a group of 20 adolescents and young adults with Friedreich's Ataxia (FA) and compared findings with a group of 20 age-equivalent and gender-matched normal control participants. State-of-the art spectral analyses from the Analysis of Dysphonia in Speech and Voice (ADSV) program, developed for various voice disorders from Kay Elemetrics, were applied to initial 2 second sustained vowel segments of the vowels /a/, /i/, and /o/. Spectral analyses included averages and standard deviations of Cepstral Peak Prominence (CPP), Cepstral Peak Prominence Standard Deviation (CPP SD), Low/High Spectral Ratio (L/H Ratio), Low/High Spectral Ratio Standard Deviation (L/H Ratio SD), Cepstral/Spectral Index of Dysphonia (CSID), and Mean Cepstral Peak Prominence Fundamental Frequency (Mean CPP F0). Statistical analyses revealed significant differences between the spectral analyses of voice characteristics of individuals with FA and those of normal controls for all measures except for CPP SD. The aim of these analyses was to determine spectral differences evident in vowel productions of individuals with FA using new cepstral-derived measures that characterize the phonatory instability and dis-coordination present in this disorder. Such research may not only help develop early non-invasive indicators of ataxia and track disease progression, but also serve to stimulate research into alleviating the symptoms of this devastating disease.

Notes

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Graduation Date

2014

Semester

Spring

Advisor

Ryalls, John

Degree

Master of Arts (M.A.)

College

College of Health and Public Affairs

Department

Communication Sciences and Disorders

Degree Program

Communication Sciences and Disorders

Format

application/pdf

Identifier

CFE0005181

URL

http://purl.fcla.edu/fcla/etd/CFE0005181

Language

English

Release Date

5-15-2019

Length of Campus-only Access

5 years

Access Status

Masters Thesis (Open Access)

Subjects

Dissertations, Academic -- Health and Public Affairs; Health and Public Affairs -- Dissertations, Academic

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