Title

Single Gene Inheritance Of Occurrence Of Head Spots In Mice

Comments

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Abbreviated Journal Title

J. Hered.

Keywords

Genetics & Heredity

Abstract

Results from earlier selection studies indicated that while the size of head spots in mice descended from the Goodale head-spot strain was a quantitative, polygenic trait, head-spot occurrence was probably a qualitative trait inherited by one or two genes. The present study was undertaken to examine this possibility by crossing a head-spot stock with three inbred strains and with two noninbred stocks carrying mutant genes. Observed segregation ratios in the F2 and backcross generations of these crosses were compared to results expected under various models of qualitative inheritance. Evidence of linkage between known loci and a putative head-spot gene also was sought. Results indicated that head spotting was inherited primarily by the action of a recessive autosomal gene, head spot (hs). The action of this gene was subject to modification, in some crosses, by other genes or by environmental factors. Attempts to demonstrate linkage between the head spots and known single-locus traits were unsuccessful.

Journal Title

Journal of Heredity

Volume

77

Issue/Number

2

Publication Date

1-1-1986

Document Type

Note

Language

English

First Page

136

Last Page

138

WOS Identifier

WOS:A1986C011800019

ISSN

0022-1503

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