Title

Inhibition of Selenium Metabolism in the Oral Pathogen Treponema denticola

Authors

Authors

S. Jackson-Rosario;W. T. Self

Comments

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Abbreviated Journal Title

J. Bacteriol.

Keywords

ANAEROBES GENUS CLOSTRIDIUM; GLYCINE REDUCTASE COMPLEX; CL.-SPOROGENES; SELENOPROTEIN COMPONENT; TRACE-ELEMENTS; DENTAL-CARIES; TIN; ACID; SELENOPHOSPHATE; IDENTIFICATION; Microbiology

Abstract

In this report we provide evidence that the antimicrobial action of stannous salts and a gold drug, auranofin, against Treponema denticola is mediated through inhibition of the metabolism of selenium for synthesis of selenoproteins.

Journal Title

Journal of Bacteriology

Volume

191

Issue/Number

12

Publication Date

1-1-2009

Document Type

Article

Language

English

First Page

4035

Last Page

4040

WOS Identifier

WOS:000266454200028

ISSN

0021-9193

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