Title
Embryonic Stem Cells in Cardiac Repair and Regeneration
Abbreviated Journal Title
Antioxid. Redox Signal.
Keywords
ACUTE MYOCARDIAL-INFARCTION; BONE-MARROW-CELLS; FUNCTIONAL IMPROVEMENT; INHIBIT APOPTOSIS; HUMAN BLASTOCYSTS; PROGENITOR CELLS; ISCHEMIC-HEART; GROWTH-FACTORS; IN-VITRO; TRANSPLANTATION; Biochemistry & Molecular Biology; Endocrinology & Metabolism
Abstract
Cell transplantation is a subject of fast-growing research with a potential of a therapeutic approach for the treatment of heart diseases. Clinical applications require preparation of large number of donor cells. Stem cell studies published to date demonstrate that scientists have not reached the general consensus to use an optimal cell type for better cardiac repair and regeneration. We used embryonic stem (ES) cells and their released factors for cardiac repair and regeneration. The major concern of cardiac regeneration with stem cells includes engraftment, differentiation, and teratoma formation after ES cell transplantation. Our current knowledge of ES cell transplantation in the heart is very limited. This review discusses the use of various growth factors to enhance ES cells engraftment and differentiation, as well as the issue of teratoma formation. Antioxid. Redox Signal. 11, 1857-1863.
Journal Title
Antioxidants & Redox Signaling
Volume
11
Issue/Number
8
Publication Date
1-1-2009
Document Type
Review
Language
English
First Page
1857
Last Page
1863
WOS Identifier
ISSN
1523-0864
Recommended Citation
"Embryonic Stem Cells in Cardiac Repair and Regeneration" (2009). Faculty Bibliography 2000s. 2154.
https://stars.library.ucf.edu/facultybib2000/2154
Comments
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