Title

Homoserine and asparagine are host signals that trigger in planta expression of a pathogenesis gene in Nectria haematococca

Authors

Authors

Z. N. Yang; L. M. Rogers; Y. D. Song; W. J. Guo;P. E. Kolattukudy

Comments

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Abbreviated Journal Title

Proc. Natl. Acad. Sci. U. S. A.

Keywords

fungal infection; pectate lyase; Pisum sativum; host-pathogen; interactions; pathogen-host coevolution; F-SP-PISI; PECTATE LYASE GENE; MATING-TYPE-VI; AMINO-ACIDS; IN-VITRO; 5'-FLANKING REGION; USTILAGO-MAYDIS; CUTINASE GENE; INFECTION; ENDOPOLYGALACTURONASE; Multidisciplinary Sciences

Abstract

Some pathogenesis-related genes are expressed in fungi only when the pathogen is in the host, but the host signals that trigger these gene expressions have not been identified. Virulent Nectria haematococca infects pea plants and requires either pelA, which is induced by pectin, or pelD, which is induced only in planta. However, the host signal(s) that trigger pelD expression was unknown. Here we report the isolation of the host signals and identify homoserine and asparagine, two free amino acids found in uniquely high levels in pea seedlings, as the pelD-inducing signals. N. haematococca has evolved a mechanism to sense the host tissue environment by using the high levels of two free amino acids in this plant, thereby triggering the expression of pelD to assist the pathogenic process.

Journal Title

Proceedings of the National Academy of Sciences of the United States of America

Volume

102

Issue/Number

11

Publication Date

1-1-2005

Document Type

Article

Language

English

First Page

4197

Last Page

4202

WOS Identifier

WOS:000227731000057

ISSN

0027-8424

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