Influence of polymer-pore interactions on translocation
Abbreviated Journal Title
Phys. Rev. Lett.
FACILITATED MEMBRANE-TRANSPORT; MONTE-CARLO-SIMULATION; POLYNUCLEOTIDE; MOLECULES; DNA TRANSPORT; NANOPORE; DRIVEN; DYNAMICS; CHANNEL; DISCRIMINATION; CHAIN; Physics, Multidisciplinary
We investigate the influence of polymer-pore interactions on the translocation dynamics using Langevin dynamics simulations. An attractive interaction can greatly improve the translocation probability. At the same time, it also increases the translocation time slowly for a weak attraction while an exponential dependence is observed for a strong attraction. For fixed driving force and chain length the histogram of translocation time has a transition from Gaussian distribution to long-tailed distribution with increasing attraction. Under a weak driving force and a strong attractive force, both the translocation time and the residence time in the pore show a nonmonotonic behavior as a function of the chain length. Our simulations results are in good agreement with recent experimental data.
Physical Review Letters
"Influence of polymer-pore interactions on translocation" (2007). Faculty Bibliography 2000s. 7385.