Title

Hemoglobin magnetism in aqueous solution probed by muon spin relaxation and future applications to brain research

Authors

Authors

K. Nagamine; K. Shimomura; H. Miyadera; Y. J. Kim; R. H. Scheicher; T. P. Das;J. S. Schultz

Comments

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Abbreviated Journal Title

Proc. Jpn. Acad. Ser. B-Phys. Biol. Sci.

Keywords

muon; muon spin relaxation; hemoglobin; blood magnetism; oxygenation; OXYHEMOGLOBIN; BLOOD; Multidisciplinary Sciences

Abstract

A marked difference in spin relaxation behavior due to hemoglobin magnetism was found for positive unions ( +) in deoxyhemoglobin in comparison with that observed in oxyhemoglobin in aqueous solution at room temperature under zero and external longitudinal magnetic fields upto 0.4 Tesla. At the same time, small but significant unique relaxation pattern was observed in nonmagnetic oxyhemoglobin. Combined with our previous measurements on hemoglobin in human blood, application of this type of measurement to the studies of the level of oxygenation in various regions of the human brain is suggested.

Journal Title

Proceedings of the Japan Academy Series B-Physical and Biological Sciences

Volume

83

Issue/Number

4

Publication Date

1-1-2007

Document Type

Article

Language

English

First Page

120

Last Page

126

WOS Identifier

WOS:000247285500003

ISSN

0386-2208

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