Title
Integration of functional myotubes with a Bio-MEMS device for non-invasive interrogation
Abbreviated Journal Title
Lab Chip
Keywords
SERUM-FREE MEDIUM; DEFINED SYSTEM; MUSCLE; CULTURE; Biochemical Research Methods; Chemistry, Multidisciplinary; Nanoscience; & Nanotechnology
Abstract
We have developed a biological micro-electromechanical system (Bio-MEMS) device consisting of surface-modified microfabricated silicon cantilevers and an AFM detection apparatus for the study of cultured myotubes. With this system we are able to selectively stimulate the myotubes as well as report on a variety of physiological properties of the myotubes in real time and in a high-throughput manner. This system will serve as the foundation for future work integrating multiple tissue types for the creation of Bio-MEMS analogues of complex tissues and biological circuits.
Journal Title
Lab on a Chip
Volume
7
Issue/Number
7
Publication Date
1-1-2007
Document Type
Article
DOI Link
Language
English
First Page
920
Last Page
922
WOS Identifier
ISSN
1473-0197
Recommended Citation
"Integration of functional myotubes with a Bio-MEMS device for non-invasive interrogation" (2007). Faculty Bibliography 2000s. 7789.
https://stars.library.ucf.edu/facultybib2000/7789
Comments
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