Abbreviated Journal Title
Antimicrob. Agents Chemother.
Keywords
CRITICALLY-ILL PATIENTS; GRAM-NEGATIVE BACTERIA; INTRAVENOUS COLISTIN; MULTIDRUG-RESISTANT; INFECTIONS; METHANESULFONATE; THERAPY; PHARMACOKINETICS; CLASSIFICATION; TOXICITY; Microbiology; Pharmacology & Pharmacy
Abstract
Thirty adult patients who received intravenous colistin (5.1 +/- 2.4 mg/kg/day) were reviewed to evaluate dosing with respect to nephrotoxicity, which occurred in 10 (33%) patients within the first 5 days of treatment. Excessive colistin dosing was frequent (47%), often (71%) resulted from the use of actual body weight in obese patients, and was associated with higher rates of nephrotoxicity (80% versus 30%, P = 0.019).
Journal Title
Antimicrobial Agents and Chemotherapy
Volume
54
Issue/Number
10
Publication Date
1-1-2010
Document Type
Article
Language
English
First Page
4503
Last Page
4505
WOS Identifier
ISSN
0066-4804
Recommended Citation
DeRyke, C. Andrew; Crawford, Amanda J.; Uddin, Nizam; and Wallace, Mark R., "Colistin Dosing and Nephrotoxicity in a Large Community Teaching Hospital" (2010). Faculty Bibliography 2010s. 108.
https://stars.library.ucf.edu/facultybib2010/108
Comments
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