Title
Toward an Integrated Knowledge Environment to Support Modern Oncology
Abbreviated Journal Title
Cancer J.
Keywords
Informatics; oncology; integration; knowledge environment; biomarkers; next-generation sequencing; patient; treatment; outcomes; ELECTRONIC HEALTH RECORDS; BREAST-CANCER; GENE-EXPRESSION; HUMAN GENOME; MEDICAL-RECORD; OVARIAN-CANCER; SEQUENCE; BIOMARKERS; CARE; BIOINFORMATICS; Oncology
Abstract
Around the world, teams of researchers continue to develop a wide range of systems to capture, store, and analyze data including treatment, patient outcomes, tumor registries, next-generation sequencing, single-nucleotide polymorphism, copy number, gene expression, drug chemistry, drug safety, and toxicity. Scientists mine, curate, and manually annotate growing mountains of data to produce high-quality databases, while clinical information is aggregated in distant systems. Databases are currently scattered, and relationships between variables coded in disparate datasets are frequently invisible. The challenge is to evolve oncology informatics from a "systems'' orientation of standalone platforms and silos into an "integrated knowledge environments'' that will connect "knowable'' research data with patient clinical information. The aim of this article is to review progress toward an integrated knowledge environment to support modern oncology with a focus on supporting scientific discovery and improving cancer care.
Journal Title
Cancer Journal
Volume
17
Issue/Number
4
Publication Date
1-1-2011
Document Type
Review
Language
English
First Page
257
Last Page
263
WOS Identifier
ISSN
1528-9117
Recommended Citation
"Toward an Integrated Knowledge Environment to Support Modern Oncology" (2011). Faculty Bibliography 2010s. 1106.
https://stars.library.ucf.edu/facultybib2010/1106
Comments
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