Nucleic Acid Detection using MNAzymes
Abbreviated Journal Title
DNA ENZYME; Biochemistry & Molecular Biology
Deoxyribozymes are promising biotechnological tools. In a recent JACS article, Mokany et al. reported on the design of multi-component deoxyribozyme (MNAzyme) sensors based on 10-23 and 8-17 DNA enzymes. The sensors can detect down to 5 pM of a specific nucleic acid. The versatility of MNAzyme platform allows the design of catalytic cascades for signal amplification. This work is a step forward to PCR-free molecular diagnostics.
Chemistry & Biology
"Nucleic Acid Detection using MNAzymes" (2010). Faculty Bibliography 2010s. 175.