Connectable DNA Logic Gates: OR and XOR Logics
Abbreviated Journal Title
DNA; logic gates; molecular beacons; molecular computing; nanotechnology; MOLECULAR BEACONS; HYBRIDIZATION KINETICS; NUCLEIC-ACIDS; CIRCUITS; PROBE; DEOXYRIBOZYME; JUNCTIONS; APTAMERS; DEVICES; DESIGN; Chemistry, Multidisciplinary
Modern computer processors are based on semiconductor logic gates connected to each other in complex circuits. This study contributes to the development of a new class of connectable logic gates made of DNA in which the transfer of oligonucleotide fragments as input/output signals occurs upon hybridization of DNA sequences. The DNA strands responsible for a logic function form associates containing immobile DNA four-way junction structures when the signal is high and dissociate into separate strands when the signal is low. A basic set of logic gates (NOT, AND, and OR) was designed. Two NOT gates, two AND gates, and an OR gate were connected in a network that corresponds to an XOR logic function. The design of the logic gates presented here may contribute to the development of the first biocompatible molecular computer.
Chemistry-an Asian Journal
"Connectable DNA Logic Gates: OR and XOR Logics" (2012). Faculty Bibliography 2010s. 2667.