Title

Unifying model of driven polymer translocation

Authors

Authors

T. Ikonen; A. Bhattacharya; T. Ala-Nissila;W. Sung

Comments

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Abbreviated Journal Title

Phys. Rev. E

Keywords

DYNAMICS; NANOPORE; MEMBRANE; Physics, Fluids & Plasmas; Physics, Mathematical

Abstract

We present a Brownian dynamics model of driven polymer translocation, in which nonequilibrium memory effects arising from tension propagation (TP) along the cis side subchain are incorporated as a time-dependent friction. To solve the effective friction, we develop a finite chain length TP formalism, based on the idea suggested by Sakaue [Phys. Rev. E 76, 021803 (2007)]. We validate the model by numerical comparisons with high-accuracy molecular dynamics simulations, showing excellent agreement in a wide range of parameters. Our results show that the dynamics of driven translocation is dominated by the nonequilibrium TP along the cis side subchain. Furthermore, by solving the model for chain lengths up to 10(10) monomers, we show that the chain lengths probed by experiments and simulations are typically orders of magnitude below the asymptotic limit. This explains both the considerable scatter in the observed scaling of translocation time with respect to chain length, and some of the shortcomings of present theories. Our study shows that for a quantitative theory of polymer translocation, explicit consideration of finite chain length effects is required.

Journal Title

Physical Review E

Volume

85

Issue/Number

5

Publication Date

1-1-2012

Document Type

Article

Language

English

First Page

7

WOS Identifier

WOS:000304064300006

ISSN

1539-3755

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