Title

Clinical Manifestations and Treatment of Drug-induced Hepatotoxicity

Authors

Authors

C. M. Giordano;X. B. Zervos

Comments

Authors: contact us about adding a copy of your work at STARS@ucf.edu

Abbreviated Journal Title

Clin. Liver Dis.

Keywords

Drug-induced liver injury; Drug-induced cholestasis; Drug-induced; hepatocellular injury; Management of drug-induced liver injury; INDUCED LIVER-INJURY; LYMPHOCYTE-TRANSFORMATION TEST; UNITED-STATES; CAUSALITY ASSESSMENT; DIAGNOSTIC SCALE; HYPERSENSITIVITY; ACETYLCYSTEINE; DISORDERS; OUTCOMES; FAILURE; Gastroenterology & Hepatology

Abstract

With an increase of prescription medication and herbal supplement use, drug-induced liver injury (DILI) has become an increasingly important entity. Because DILI is a usually readily treatable condition, it is essential for providers to reach a diagnosis in a timely fashion. Unfortunately, varied clinical presentations, difficulties in establishing causality, and lack of a gold standard diagnostic criterion may make early diagnosis difficult. This article seeks to define commonly used terminology, describe common clinical presentations of DILI, provide an overview of current diagnostic criteria, and provide management guidelines.

Journal Title

Clinics in Liver Disease

Volume

17

Issue/Number

4

Publication Date

1-1-2013

Document Type

Article

Language

English

First Page

565

Last Page

+

WOS Identifier

WOS:000326659500006

ISSN

1089-3261

Share

COinS