The need for a disease-specific prospective pregnancy registry for multiple sclerosis (MS)
Abbreviated Journal Title
Mult. Scler. Relat. Disord.
Multiple sclerosis; Pregnancy; Reproduction; Birth outcome; Pregnancy; registry; GLATIRAMER ACETATE EXPOSURE; MYCOPHENOLATE-MOFETIL; MITOXANTRONE; EXPOSURE; HUMAN TERATOGENICITY; DIAGNOSTIC-CRITERIA; INTERFERON BETA-1B; CONTROLLED-TRIAL; MODIFYING DRUGS; BIRTH OUTCOMES; FETAL OUTCOMES; Clinical Neurology
Multiple sclerosis (MS) is the most commonly acquired neurological disorder affecting young adults of reproductive age with an approximately 3:1 female to male ratio. Although pregnancy is not contraindicated in MS, data are limited regarding pregnancy outcome among MS patients, and the safety or risk to the fetus associated with most maternal MS treatments, such as disease modifying therapies (DMTs), during pregnancy is unknown. We review available epidemiological and registry data on MS and pregnancy and discuss the need to initiate a North American Multiple Sclerosis Pregnancy Registry that will prospectively identify pregnancies in women with MS, obtain information on the disease, and its treatment during gestation and lactation and follow the children to determine their health status. (C) 2014 Elsevier B.V. All rights reserved.
Multiple Sclerosis and Related Disorders
"The need for a disease-specific prospective pregnancy registry for multiple sclerosis (MS)" (2015). Faculty Bibliography 2010s. 6392.