Title

beta-Hydroxy-beta-methylbutyrate (HMB) supplementation and resistance exercise significantly reduce abdominal adiposity in healthy elderly men

Authors

Authors

J. R. Stout; D. H. Fukuda; K. L. Kendall; A. E. Smith-Ryan; J. R. Moon;J. R. Hoffman

Comments

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Abbreviated Journal Title

Exp. Gerontol.

Keywords

Aging; Abdominal fat mass; Exercise; beta-Hydroxy-beta-methylbutyrate; X-RAY ABSORPTIOMETRY; INSULIN SENSITIVITY; RELIABILITY; ADULTS; FAT; Geriatrics & Gerontology

Abstract

The effects of 12-weeks of HMB ingestion and resistance training (RT) on abdominal adiposity were examined in 48 men (66-78 yrs). All participants were randomly assigned to 1 of 4 groups: no-training placebo (NT-PL), HMB only (NT-HMB), RT with PL (RT-PL), or HMB with RT (RT-HMB). DXA was used to estimate abdominal fat mass (AFM) by placing the region of interest over the L1-L4 region of the spine. Outcomes were assessed by ANCOVA, with Bonferroni-corrected pairwise comparisons. Baseline AFM values were used as the covariate. The ANCOVA indicated a significant difference (p = 0.013) between group means for the adjusted posttest AFM values (mean (kg) +/- SE: NT-PL = 2.59 +/- 0.06; NT-HMB = 2.59 +/- 0.61; RT-PL = 2.59 +/- 0.62; RT-HMB = 2.34 +/- 0.61). The pairwise comparisons indicated that AFM following the intervention period in the RT-HMB group was significantly less than NT-PL (p = 0.013), NT-HMB (p = 0.011), and RT-PL (p = 0.010). These data suggested that HMB in combination with 12 weeks of RT decreased AFM in elderly men. (C) 2015 Elsevier Inc. All rights reserved.

Journal Title

Experimental Gerontology

Volume

64

Publication Date

1-1-2015

Document Type

Article

Language

English

First Page

33

Last Page

34

WOS Identifier

WOS:000350812800004

ISSN

0531-5565

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