Abstract

Methods are described that bias cells, such as potent and multipotent stem cells, by transfection with a nucleic acid sequence, to differentiate to a desired end-stage cell or a cell having characteristics of a desired end-stage cell. In particular embodiments, human neural stem cells are transfected with vectors comprising genes in the homeobox family of transcription factor developmental control genes, and this results in a greater percentage of resultant transformed cells, or their progeny, differentiating into a desired end-stage cell or a cell having characteristics of a desired end-stage cell.

Document Type

Patent

Patent Number

US 9,127,291

Application Serial Number

13/969,799

Issue Date

9-8-2015

Current Assignee

UCFRF

Assignee at Issuance

UCFRF

College

Burnett School of Biomedical Sciences

Department

Biomolecular Science Center

Allowance Date

4-20-2015

Filing Date

8-19-2013

Assignee at Filing

UCFRF

Filing Type

Nonprovisional Application Record

Donated

no

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