We propose a method of expanding stem cells and dedifferentiating cells by cultruing cells with cell cultrue extracts of embryonic stem cellas and or extracts from a regenerating limb. We demonstrated that co cultureing human bone marrow mesenchymal stem cells with sections of a lizard tail or mouse embryonic stem cells increases the stemness of the Msc. This allows for the creation of a cell cultruing system containing expgenous factors that facilitate increased expression of stem cells genes and dedifferentiation.
Application Serial Number
Assignee at Issuance
Burnett School of Biomedical Sciences
Biomolecular Science Center
Assignee at Filing
Nonprovisional Application Record
Sugaya, Kiminobu and Alvarez, Angel, "Methods for modifying stem cell characteristics" (2012). UCF Patents. 376.