Abstract
A method of testing bacterial cells for antimicrobial susceptibility includes preparing a suspension of the bacterial cells in a non-nutrient medium, mixing with the suspension an antimicrobial, a carbohydrate usable by the bacterial cells, metallic nanoparticles, and a lectin, and incubating the mixture while monitoring a parameter of the nanoparticles responsive to use of the carbohydrate by the bacterial cells. More broadly stated, the invention includes a method of testing an agent for its effect on cell metabolism by preparing a suspension of cells in a non-nutrient medium, mixing the suspension with the agent, adding a carbohydrate usable by the cells, metallic nanoparticles, and a lectin with binding specificity for the added carbohydrate, and monitoring a nanoparticle parameter responsive to the cells.
Document Type
Patent
Patent Number
US 9,057,094
Application Serial Number
12/258,785
Issue Date
6-16-2015
Current Assignee
UCFRF
Assignee at Issuance
UCFRF
College
NanoScience Technology Center
Department
NanoScience Technology Center
Allowance Date
2-11-2015
Filing Date
10-27-2008
Assignee at Filing
UCFRF
Filing Type
Nonprovisional Application Record
Donated
no
Recommended Citation
Perez Figueroa, J. Manuel; Kaittanis, Charalambos; and Nath, Sudip, "Nanoparticle-Mediated Methods for Antimicrobial Susceptibility Testing of Bacteria" (2015). UCF Patents. 410.
https://stars.library.ucf.edu/patents/410