Methods and systems for doping cerium oxide and other therapeutically valuable nanoparticles with rare earth ions either singly or in combinations so that infrared light is absorbed and visible light is emitted through the process of up conversion. A novel type of therapeutic nanoparticle with rare earth doping to provide for up conversion emission is invented that makes possible identification, tracking and evaluating the functionality of the nanoparticles and further elucidation of ROS scavenging mechanism. The present invention may be applied to a wide variety of therapeutic agents under investigation.
US 9,127,202 B1
Application Serial Number
Assignee at Issuance
College of Optics and Photonics
Assignee at Filing
Nonprovisional Application Record
Bass, Michael; Seal, Sudipta; and Self, William, "Biocompatible Nano Rare Earth Oxide Upconverters for Imaging and Therapeutics" (2015). UCF Patents. 53.