This invention is directed to methods and compositions for inhibiting caspase-independent apoptosis. In particular, methods and compositions for inhibiting Omi/HtrA2 activity, as well as method for identifying other inhibitors of Omi/HtrA2. Also disclosed are Omi/HtrA2 specific substrates and methods for identifying other substrates of Omi/HtrA2.
US 8,242,122 B2
Application Serial Number
Assignee at Issuance
Burnett School of Biomedical Sciences
Molecular Biology & Microbiology
Assignee at Filing
Nonprovisional Application Record
Zervos, Antonis, "Methods and compounds for inhibition of cell death" (2012). UCF Patents. 753.