Abstract
This invention is directed to methods and compositions for inhibiting caspase-independent apoptosis. In particular, methods and compositions for inhibiting Omi/HtrA2 activity, as well as method for identifying other inhibitors of Omi/HtrA2. Also disclosed are Omi/HtrA2 specific substrates and methods for identifying other substrates of Omi/HtrA2.
Document Type
Patent
Patent Number
US 8,242,122 B2
Application Serial Number
12/751,036
Issue Date
8-14-2012
Current Assignee
UCFRF
Assignee at Issuance
UCFRF
College
Burnett School of Biomedical Sciences
Department
Molecular Biology & Microbiology
Allowance Date
4-12-2012
Filing Date
3-31-2010
Assignee at Filing
UCFRF
Filing Type
Nonprovisional Application Record
Donated
no
Recommended Citation
Zervos, Antonis, "Methods and compounds for inhibition of cell death" (2012). UCF Patents. 753.
https://stars.library.ucf.edu/patents/753
COinS