Abstract

Disclosed herein are methods and materials for producing a more developmentally potent cell from a less developmentally potent cell. Specifically exemplified herein are methods that comprise introducing an expressible dedifferentiating polynucleotide sequence into a less developmentally potent cell, wherein the transfected less developmentally potent cell becomes a more developmentally potent cell capable of differentiating to a less developmentally potent cell of its lineage of origin or a different lineage.

Document Type

Patent

Patent Number

US 8,192,988 B2

Application Serial Number

11/258,401

Issue Date

6-5-2012

Current Assignee

UCFRF

Assignee at Issuance

UCFRF

College

Burnett School of Biomedical Sciences

Department

Biomolecular Science Center

Allowance Date

4-26-2012

Filing Date

10-24-2005

Assignee at Filing

UCFRF

Filing Type

Nonprovisional Application Record

Donated

no

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