Disclosed herein are methods and materials for producing a more developmentally potent cell from a less developmentally potent cell. Specifically exemplified herein are methods that comprise introducing an expressible dedifferentiating polynucleotide sequence into a less developmentally potent cell, wherein the transfected less developmentally potent cell becomes a more developmentally potent cell capable of differentiating to a less developmentally potent cell of its lineage of origin or a different lineage.
US 8,192,988 B2
Application Serial Number
Assignee at Issuance
Burnett School of Biomedical Sciences
Biomolecular Science Center
Assignee at Filing
Nonprovisional Application Record
Sugaya, Kiminobu and Alvarez, Angel, "Methods for increasing potency of adult mesenchymal stem cells" (2012). UCF Patents. 754.