Keywords

Coronary heart disease, Immunopathology, Milk

Abstract

Milk protein has been implicated as a factor in the development of atherosclerosis. Significantly higher titers of antibodies (P < 0.0002) toward milk antigens were observed in patients suffering from coronary heart disease as compared to age matched controls. These hemagglutination titers were not sex related but may have been related to age. Specificity of the antigen-antibody reaction was demonstrated by a hemagglutination inhibition test. The complement fixation test was evaluated and was less sensitive than the tanned hemaggIutination test. Treatment with 2-mercapto-ethanol resulted in reduced hemagglutination titers, indicating that significant antibody activity may be due to IgM. A special application of the Combs test detected specific antibodies on the surface of tanned and coated RBC which did not otherwise produce detectable agglutination.

Graduation Date

1977

Advisor

Sweeney, Michael J.

Degree

Master of Science (M.S.)

College

College of Natural Sciences

Degree Program

Biology

Format

PDF

Pages

iv, 57 pages

Language

English

Rights

Written permission granted by copyright holder to the University of Central Florida Libraries to digitize and distribute for nonprofit, educational purposes.

Length of Campus-only Access

None

Access Status

Masters Thesis (Open Access)

Identifier

DP0003521

Subjects

Coronary heart disease, Immunopathology, Milk

Collection (Linked data)

Retrospective Theses and Dissertations

Included in

Biology Commons

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