Keywords

Acceleration (Physiology), Aeronautics -- Research, Proteins -- Research, Space flight -- Physiological effect, Space medicine

Abstract

Laboratory and feral lineages of mice were subjected to cephalad (+GZ) accelerations, for 1.8 seconds, aboard a solid fuel rocket. Spectrophotometric analysis of bronchoalveolar lavage retrieved post launch revealed significant (p < .001) elevations of protein in the lungs of experimental mice. Sudden transient imposition of a mean +GZ acceleration of 6.22±.47 (SD) G, at lift-off, may have induced hypervolemia of basilar pulmonary microvasculature with concomitant migration of fluid and protein from intravascular to juxta-alveolar perivascular compartments. Exudates may have entered bronchiolar airways subsequently gravitating toward alveoli.

Notes

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Graduation Date

1985

Semester

Spring

Advisor

Crittenden, Daniel J.

Degree

Master of Science (M.S.)

College

College of Health

Degree Program

Health Sciences

Format

PDF

Language

English

Rights

Public Domain

Length of Campus-only Access

None

Access Status

Masters Thesis (Open Access)

Identifier

DP0017160

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