Acceleration (Physiology), Aeronautics -- Research, Proteins -- Research, Space flight -- Physiological effect, Space medicine
Laboratory and feral lineages of mice were subjected to cephalad (+GZ) accelerations, for 1.8 seconds, aboard a solid fuel rocket. Spectrophotometric analysis of bronchoalveolar lavage retrieved post launch revealed significant (p < .001) elevations of protein in the lungs of experimental mice. Sudden transient imposition of a mean +GZ acceleration of 6.22±.47 (SD) G, at lift-off, may have induced hypervolemia of basilar pulmonary microvasculature with concomitant migration of fluid and protein from intravascular to juxta-alveolar perivascular compartments. Exudates may have entered bronchiolar airways subsequently gravitating toward alveoli.
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Crittenden, Daniel J.
Master of Science (M.S.)
College of Health
Length of Campus-only Access
Masters Thesis (Open Access)
Gutierrez, Charles J., "Protein Concentration Elevations in Mouse Lung Following Sudden Transient Cephalad (+Gz)" (1985). Retrospective Theses and Dissertations. 4785.