The Preparation Of Aromatic Amidino Esters And Their Reaction With Primary Amines
Abbreviated Journal Title
A series of aromatic amidino esters were prepared from the respective anthranilic acids by reaction with DMF acetal. These amidino esters were then condensed with a variety of primary amines to give the corresponding 3-substituted quinazolin-4-ones. Based on substituent effects, and the application of acid catalysis, a unifying mechanism is proposed.
Gupton, John T.; Miller, John F.; Bryant, Robert D.; Maloney, Patrick R.; and Foster, Bruce S., "The Preparation Of Aromatic Amidino Esters And Their Reaction With Primary Amines" (1987). Faculty Bibliography 1980s. 870.