Anticancer and antithrombin activity of Russian plants
Abbreviated Journal Title
antithrombin activity; anticancer activity; mouse leukemia (L1210); Russian plants; Quercus robur; Sanguisorba officinalis; TANACETUM-VULGARE L; ANTIOXIDATIVE ACTIVITY; ROSMARINIC ACID; SESQUITERPENE; CONSTITUENTS; LAMIACEAE; SKELETON; LACTONE; Plant Sciences; Chemistry, Medicinal; Integrative & Complementary; Medicine; Pharmacology & Pharmacy
A chromogenic bioassay was utilized to determine the antithrombin activity of the methylene chloride and methanol extracts prepared from forty-five plants of Russia. Mouse leukemia cells (L1210) were utilized to screen these extracts for activity against cancer. The results indicated that eight plant extracts demonstrated 90% or higher activity in the inhibition of thrombin. Also, nine methanol extracts demonstrated activity of 90% or higher in the inhibition of mouse leukemia L1210 cells. The methanol extracts of Quercus robur and Sanguisorba afficinalis demontrated high activity against both thrombin and cancer. (C) 2002 Elsevier Science Ireland Ltd. All rights reserved.
Journal of Ethnopharmacology
"Anticancer and antithrombin activity of Russian plants" (2002). Faculty Bibliography 2000s. 3232.