Title

Tyrosine nitration as mediator of cell death

Authors

Authors

M. C. Franco;A. G. Estevez

Comments

Authors: contact us about adding a copy of your work at STARS@ucf.edu

Abbreviated Journal Title

Cell. Mol. Life Sci.

Keywords

Tyrosine nitration; Cell death; Reactive nitrogen species; Peroxynitrite; Nitrated Hsp90; MANGANESE-SUPEROXIDE-DISMUTASE; PEROXYNITRITE-INDUCED APOPTOSIS; AMYOTROPHIC-LATERAL-SCLEROSIS; NITRIC-OXIDE SYNTHASE; LIVER; PLASMA-MEMBRANE; SPINAL-CORD-INJURY; DEPENDENT PROTEIN NITRATION; ALZHEIMERS-DISEASE BRAIN; OXIDATIVE STRESS; CYTOCHROME-C; Biochemistry & Molecular Biology; Cell Biology

Abstract

Nitrotyrosine is used as a marker for the production of peroxynitrite and other reactive nitrogen species. For over 20 years the presence of nitrotyrosine was associated with cell death in multiple pathologies. Filling the gap between correlation and causality has proven to be a difficult task. Here, we discuss the evidence supporting tyrosine nitration as a specific posttranslational modification participating in the induction of cell death signaling pathways.

Journal Title

Cellular and Molecular Life Sciences

Volume

71

Issue/Number

20

Publication Date

1-1-2014

Document Type

Article

DOI Link

http://dx.doi.org/10.3390/su5114674

Language

English

First Page

3939

Last Page

3950

WOS Identifier

WOS:000342420300005

ISSN

1420-682X

Recommended Citation

"Tyrosine nitration as mediator of cell death" (2014). Faculty Bibliography 2010s. 2592.
https://stars.library.ucf.edu/facultybib2010/2592