Selective Fluorescence Sensing of Zinc and Mercury Ions with Hydrophilic 1,2,3-Triazolyl Fluorene Probes
Abbreviated Journal Title
ABSORPTION CROSS-SECTION; HEAVY-METAL IONS; ONE-PHOTON; 2-PHOTON; EXCITATION; CLICK CHEMISTRY; DERIVATIVES; SENSOR; PHOTOSTABILITY; MONOLAYERS; PHYSIOLOGY; Chemistry, Physical; Materials Science, Multidisciplinary
The ability to rapidly detect biologically and environmentally significant metal ions such as zinc and mercury is important to study a number of important cellular and environmental processes. Hydrophilic bis(1,2,3-triazolyl)fluorene-based derivatives containing a 1,2,3-triazole-based recognition moiety were synthesized through Click chemistry and characterized by UV vis absorption, fluorescence emission, and two-photon absorption as new fluorescence sensing probes, selective for Zn(2+) and Hg(2+) ions. The UV vis absorption and fluorescence emission spectra of the complexes exhibited blue-shifted absorption and emission spectra upon chelation to Zn(2+) and Hg(2+) ions, resulting in ca. 2-fold enhancement in fluorescence. Fluorometric titration revealed that 1:2 and 1:3 ligand to metal complexes formed with binding constants of 10(8) and 10(16) for Zn(2+) and Hg(2+), respectively. The two-photon absorption cross sections for the probes and probe-metal ion complexes ranged from 200 to 350 GM at 800 nm. These novel fluorescent compounds may have potential as new metal ion sensors to probe cellular and biological environments.
Chemistry of Materials
"Selective Fluorescence Sensing of Zinc and Mercury Ions with Hydrophilic 1,2,3-Triazolyl Fluorene Probes" (2010). Faculty Bibliography 2010s. 591.