A collection of Medicine Masters Theses and Doctoral Dissertations.
Theses/Dissertations from 2023
Polyamine Blockade Therapy: Modulating Pancreatic Tumor Microenvironment and Role in MDSC Biology, Manav Gandhi
Host Cell Responses Modulate Oncolytic Viral Treatment of Neuroblastoma Cells, Kritika Kedarinath
Identification of an Endogenous Multiprotein Complex Required to Generate the VLDL Transport Vesicle from the Hepatic ER, Rutuparnna Mishra
GATM is Involved in the Promotion of Drug Resistance in Lung Cancer, Nikitha Murugavel
Mechanisms of Early-Stage Mutant EGFR-Driven Lung Cancer: The Role of Kynurenine, Alice Rodriguez-Fuguet
Preclinical Assessment of Psychoplastogens for Treatment of Psychiatric Symptoms and Neuroplasticity Deficits in Huntington Disease, Nicholas Skiados
Role of Vitamin D, Folate, and Cobalamin Deficiency in Mycobacterium avium Paratuberculosis Infection and Inflammation, Joseph Vaccaro
Impact of R300 and C343 in the B' Domain of Protein Disulfide Isomerase on its Disaggregase Activity Against Cholera Toxin, Evie Vincent
Theses/Dissertations from 2022
Delineating the Cytotoxic Mechanism of Purine Metabolite AICAR in Lung Cancer Cells, Fareesa Aftab
Extracellular Vesicle-associated Biomolecules as Potential Biomarkers for Alzheimer's Disease Diagnosis, Lina Bedoya Martinez
Discovery of Antiplasmodial Compounds From Fungi, Jennifer Collins
Chaperonin Containing TCP-1 is a novel biomarker for cancer detection, Amanda Cox
3D Microelectrode Arrays (MEAs) For The Study And Interrogation Of Electrogenic Cells In Fabricated Microenvironments, Charles Didier
Development of Curcumin-loaded Nanoparticles for Drug Delivery Optimization in the Treatment of Peripheral Nerve Injury, Giuliana Giannelli
Molecular Adaptations for Intestinal Colonization in Vibrio cholerae, Trudy-Ann Grant
Evaluation of Magnesium Hydroxide Particles Coated with Betaine and Citrate as a Magnesium Delivery System for Migraine Treatment, Ashton Holderness
Reexamining Cytolethal Distending Toxin's Host Cell Entry and Trafficking: The First Steps Down a Long Road, George Huhn
Effects of PCSK9i on Doxorubicin Induced Necroptosis, Omonzejie Imaralu
Functional Based Drug Discovery With Artificial Intelligence, Arash Keshavarzi Arshadi
Reporter Chondrocyte Optimization of Bioinks for Zonal 3D Bioprinting of Cartilage, Kari Martyniak
Investigating the Relationship Between the Microbiome and Neuroactive Metabolites in Huntington Disease Model Mice, Christian Millot
Topographical Distribution and Morphology of Substance P Containing Nerves in the Flat-Mounts and Serial Sections of Mouse Whole Stomach at the Single Cell/Axon/Synapse Scale: A Comprehensive Study., Anas Jaser Mousa Mistareehi
Evaluating Novel Combinations of Polyamine Targeting Therapeutics in Pancreatic Ductal Adenocarcinoma, Sai Preethi Nakkina
Mapping the Organization and Morphology of Calcitonin Gene-Related Peptide (CGRP)-IR Axons in the Whole Mouse Stomach, Duyen Nguyen
The Role of Pro-Longevity MicroRNAs in Aging, Sarah Noureddine
Deciphering the Role and Clinical Application of the FGFR4-KLB-FGF19 Axis in Colorectal Neoplastic Progression, Michael Rohr
BMP-7 Ameliorates Ponatinib Induced Muscle Cell toxicity: An in vitro and in vivo Study, Ayushi Srivastava
Virus Mediated Delivery of Signals to Enhance NK Cell Mediated Killing of Tumor Cells, Namita Varudkar
Computational Strain Analysis in Microbiome Datasets with Application to Skin Disease, Minerva Fatimae Ventolero
Intrahost Diversity of Staphylococcus aureus in Carriage among Native Americans, Julia Webb
Theses/Dissertations from 2021
Downregulation of miR-34a via Calorie Restriction Regulates Lipid Metabolism in the Liver of Long-living Ames Dwarf Mice, Sarah Ashiqueali
Investigating the Role of the Skeletal Muscle in Amyotrophic Lateral Sclerosis Neuromuscular Junction Dysfunction, Agnes Badu-Mensah
Chitosan-Gallium Nanocomposite: Synthesis, Characterization and Antibacterial Activity, Samjhana Bhandari
Modulation of Fat Taste by Diet and Hormones, Ashley Calder
Regulation of Actin Assembly, Mechanics, and Structure by Intracellular Environmental Factors, Nicholas Castaneda
Sex Differences in Peripheral Fat Detection and Metabolism, Naima Dahir
Doxorubicin-Induced Differential Patterns of Cell Death in the Skeletal Muscle, Fatima Bianca Dessouki
Reassessing the Transcriptional Regulation of Protective CD4 T Cell Responses Against Influenza A Virus, Kunal Dhume
Development of Adjunctive Agents for Difluoromethylornithine Anti-cancer Therapy, Aiste Dobrovolskaite
The Consequence of Loss of Expression of AR-targeting MicroRNAs in Prostate Cancer Progression, Kavya Ganapathy
Chaperonin-containing TCP1 Complex (CCT) Promotes Breast Cancer Uncontrolled Growth, Heba Ghozlan
Novel Mechanisms Underlying Drug-resistant Metastasis and Relapse in Breast Cancer, Jie Hao
Influence of Geography on the Healthy Gut Microbiome and the Role of the Gut Microbiome in IBD Symptom and Disease Progression, Sayf Al-Deen Hassouneh
Investigating Effects of Ribosomal Occupancy on the Production of the Clamp Loader Subunits Tau and Gamma, Akhmetzada Kargazhanov
Effects of Endogenous E. coli Molecules on Translational Fidelity, Piotr Lagod
Bacterial Association Networks from Healthy and Cancer-associated Gut Microbiomes, Mark Loftus
Utilization of HBPE Nanoparticles for Optimizing Drug Delivery to Cancer Cells, Daniel Nierenberg
Competence Transcriptome Changes in Streptococcus Pneumoniae, Smitha Shambhu
Theses/Dissertations from 2020
Optimization of Cryopreserved Memory CD4 T Cell Mediated Protection against Lethal Influenza A Virus Infection in Mice, Fahmida Alam
Copper/N-acetylcysteine Coated Iron Oxide Nanoparticles Synthesis, Characterization, and Antimicrobial Activities, Danya Belnour
HIV Infection in Women: Novel Approaches for Prevention, Michelle Cherne
Early Host Defense Mechanisms against La Crosse Virus Infection, Maria A. Cruz Zamora
Single Cell Forensic Genomics - DNA Profiling of Micromanipulated Single Spermatozoa, Haley Hardin
Gelsolin-Mediated Actin Filament Severing in Crowded Environments, James Heidings
The Role of Notch1, IL-6 and miR-146a in Inflammation and Infection in Crohn's Disease Non-Responders to Anti-TNF-Alpha Therapy, Esra'a Keewan
Mapping of the Rat Intrinsic Cardiac Nervous System in 3D Reconstructed Hearts, Clara Leung
The Innate Immune Response to House Dust Mite in Allergic Airway Inflammation, Madelyn Miller
Identification of Novel Antimalarials From Natural Product Inspired Libraries, David Perry
Novel Roles of RIP2 in Inflammation and Resolution, Michael Shehat
Chaperonin-containing TCP-1 Modulates Breast Cancer Growth and Malignancy, Anne Showalter
Theses/Dissertations from 2019
AB Toxins: Recovery from Intoxication and Relative Potencies, Patrick Cherubin
Alpha-Tocopherol Reduces VLDL Secretion Through Modulation of the VLDL Transport Vesicle, Ryan Clay
A Cytoplasmic-Replicating RNA Virus Sensitizes Cancer Cells to DNA Modifying Agents, Candace Fox
Multi-target High-throughput Screening Assays for Antimicrobial Drug Discovery, Christopher Grube
Unraveling PDI and its Interaction with AB Toxins, Jessica Guyette
Identification and Functional Characterization of a Long Non-coding RNA associated with Prostate Cancer, Md Faqrul Hasan
ATP Induced Molecular Disassembly of Cytolethal Distending Toxin's B/C Heterodimer, George Huhn
Synthesis and Bioevaluation of Methionine Depletion Agents, Houssine Ikhlef
Phenotypic and Molecular Characterization of the Emergent Marine Pathogen Vibrio vulnificus, Jane Maureen Jayakumar
Selenium vs. Sulfur: Investigating the Substrate Specificity of a Selenocysteine Lyase, Michael Johnstone
It Takes Two to Tango: The Toxin-chaperone Relationship, Alisha Kellner
Use of Artificial Intelligence for Malaria Drug Discovery, Arash Keshavarzi Arshadi
Zika Virus-induced Lysis of Cervical Cancer Cells, Harini Krishnapura
Unraveling the Role of Phenylethanolamine N-methyltransferase (Pnmt+) Cells In-vivo, Sanjana Manja
Motor and Sensory Characterization of a Mouse Model of Charcot-Marie-Tooth Type 2O Disease, Swaran Nandini
Allelic Characterization and Novel Functions of the Outer Membrane Porin U in Vibrio Cholerae, Sk Nazmus Sakib
Metabolic Effects of 17a-Estradiol are Growth Hormone Independent and Sex Specific, Silvana Sidhom
Mechanism of NANOGP8 in Glioblastoma Multiforme, Jonhoi Smith
Biochemical Characterization of Rv2633c from Mycobacterium tuberculosis and the Effects of Mutagenesis on Iron Binding, Kyle Strickland
Investigating Changes in Quiescence in Oral and Esophageal Epithelium in Response to Injury, Alexandra Troia
Theses/Dissertations from 2018
Development of a Functional In Vitro 3D Model of the Peripheral Nerve, Wesley Anderson
Regulation of Extra-Pituitary Prolactin in Monocytes and Macrophages, Richard Barrett
Knowledge and Attitudes Regarding the Recent Zika Outbreak Among a Sample of South Florida Residents, Mohamed Elakkari
Dissecting the Components of Neuropathic Pain, Dale George
Embryonic Stem Cell Derived Exosomes Enhance Cardiac Stem Cell Differentiation into Heart Cells, Jamillah Hammond
Role of Mycobacterium avium paratuberculosis (MAP) and TNFSF15 SNPs on TL1A in CD, Sayf Al-Deen Hassouneh
Development of a Non-Human Primate Model for Staphylococcus aureus Nasal Carriage, Amanda Lasseter