Abstract

Disclosed are progestin agonists having the following formula: ##STR1## W is absent or --CH-CH--; R1 are independently selected from the group consisting of halogen, --CF3, and NO2, or both R1 may be joined to form a bi-radical which is --CH-CHCH-CH--;R3 are independently selected from the group consisting of hydrogen, C1-6 branched or linear alkyl, halogen and --CF3, with the proviso that R3 at the 3-position must be H where R3 at the 4-position is H, or both R3 may be joined to form a bi-radical selected from the group consisting of --CH-CHCH-CH--, --C(NC1-4 alkyl2)=CHCH-CH-- and --(CH2)4 --; R5 is selected from the group consisting of H and Me; with the proviso that only one of R1 and R3 forms the fused bi-radical; and the stereoisomers.

Document Type

Patent

Patent Number

US 8,362,476

Application Serial Number

12/726,545

Issue Date

1-29-2013

Current Assignee

UCFRF

Assignee at Issuance

UCFRF

College

College of Optics and Photonics

Department

CREOL

Allowance Date

12-14-2012

Filing Date

3-18-2010

Assignee at Filing

UCFRF

Filing Type

Nonprovisional Application Record

Donated

no

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