Abstract
The invention provides a composition comprising a plurality of nanoceria particles, a sufficient amount of at least one inhibitor of human carbonic anhydrase II associated with said plurality of nanoceria particles, and a pharmaceutically acceptable carrier containing said plurality of nanoceria particles with associated inhibitor. One preferred inhibitor of human carbonic anhydrase II comprises 4-carboxybenzene sulfonamide. The disclosed composition is useful in treatment of glaucoma.
Document Type
Patent
Patent Number
US 8,795,737
Application Serial Number
13/724,750
Issue Date
8-5-2014
Current Assignee
Joint Assignment w/UCFRF: North Dakota State University
Assignee at Issuance
Joint Assignment w/UCFRF: North Dakota State University
College
Advanced Materials Processing & Analysis Center (AMPAC)
Department
Advanced Materials Processing & Analysis Center (AMPAC)
Allowance Date
3-31-2014
Filing Date
12-21-2012
Assignee at Filing
Joint Assignment w/UCFRF: North Dakota State University
Filing Type
Nonprovisional Application Record
Donated
no
Recommended Citation
Seal, Sudipta; Haldar, Manas; Mallik, Sanku; and Patil, Swanand, "Functionalized Nanoceria Composition for Ophthalmic Treatment DIV 2" (2014). UCF Patents. 202.
https://stars.library.ucf.edu/patents/202