Abstract

Proper cellular functionand development depends on intrinsic signals and extracellular environmental cues. The interplay of these environmental influences and intracellular dynamics determine cellular ectivity including migration, differentiation and the manner in whihc it interacts with surrounding cells. An object of this invention invloves a way to mofigy cellular activity by gene insertion. Another object of this invention is the application of specially modified cells for therapeutic and research applications. Through gene insertion by means of a delivery system such as transfection we can create specialized cell types from various stem cells including adults these cells can be either be used to deliver proteins to a particular area in the body or develop into specialized cells. Examples include inner ear hair cells, cholinergic neurons or improved stem cells.

Document Type

Patent

Patent Number

US 8,080,420

Application Serial Number

11/258,603

Issue Date

12-20-2011

Current Assignee

UCFRF

Assignee at Issuance

UCFRF

College

Burnett School of Biomedical Sciences

Department

Biomolecular Science Center

Allowance Date

8-15-2011

Filing Date

10-24-2005

Assignee at Filing

UCFRF

Filing Type

Nonprovisional Application Record

Donated

no

Download Patent

Share

COinS