Title

Milestones In Chloroplast Genetic Engineering: An Environmentally Friendly Era In Biotechnology

Abstract

Chloroplast genomes defied the laws of Mendelian inheritance at the dawn of plant genetics, and continue to defy the mainstream approach to biotechnology, leading the field in an environmentally friendly direction. Recent success in engineering the chloroplast genome for resistance to herbicides, insects, disease and drought, and for production of biopharmaceuticals, has opened the door to a new era in biotechnology. The successful engineering of tomato chromoplasts for high-level transgene expression in fruits, coupled to hyper-expression of vaccine antigens, and the use of plant-derived antibiotic-free selectable markers, augur well for oral delivery of edible vaccines and biopharmaceuticals that are currently beyond the reach of those who need them most.

Publication Date

2-1-2002

Publication Title

Trends in Plant Science

Volume

7

Issue

2

Number of Pages

84-91

Document Type

Review

Personal Identifier

scopus

DOI Link

https://doi.org/10.1016/S1360-1385(01)02193-8

Socpus ID

0036481848 (Scopus)

Source API URL

https://api.elsevier.com/content/abstract/scopus_id/0036481848

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