Morphometric Vertebral Fractures And Their Relationship With 25 Oh-Vitamin D, Body Mass Index, And Age In Elderly Women

Keywords

Age; Body mass index; Vertebral fracture; Vitamin D

Abstract

Objective: To determine the presence of morphometric vertebral fractures, as well as their relationship with 25 OH Vitamin D, body mass index, and age in elderly women. Materials and methods: A cross-sectional study was conducted on 319 elderly women from the study 'Musculoskeletal Health in the Elderly'. The morphometric determination of vertebral fractures was performed with radiography, while the levels of 25 OH Vitamin D were determined by the chemiluminescent immunoassay (CLIA) method using the Liaison® 25 OH Vitamin D Total Assay 25 (Ref 310 600), using the Liaison® Analyser. The body mass index was obtained as recommended by the World Health Organisation; weight in kilograms over height in metres squared. The age of the participants was verified by their identity card, and their income details from the national data bases (SISPRO-FOSYGA). Results: The mean age was 74.3 years (SD ± 7.2). The overall prevalence of fractures was 17.9%; 54.9% of participants had values between 20 and 29ng/ml 25 OH Vitamin D, and 58.9% had body mass index values less than 25kg/m2. The mean 25 OH Vitamin D was lower in participants with fractures (19.7 vs. 25.1) (P <.05). Body mass index was also lower in those with fractures (23.5 vs. 24.6) (P <.05), but age was higher: 78.9 vs. 73.4 (P <.05). When comparing the mean levels of 25 OH Vitamin D in fractured and non-fractured participants, significantly lower levels of 25 OH Vitamin D were found in participants with fractures over 69 years-old, and on comparing the body mass index, the values of 25 OH Vitamin D were significantly lower in each of the categories of participants with a fracture. Conclusion: A statistically significant relationship was found between morphometric vertebral fractures and: 1) low levels of 25 OH Vitamin D, 2) being older and, and 3) a lower body mass index.

Publication Date

10-1-2016

Publication Title

Revista Colombiana de Reumatologia

Volume

23

Issue

4

Number of Pages

229-235

Document Type

Article

Personal Identifier

scopus

DOI Link

https://doi.org/10.1016/j.rcreu.2016.06.007

Socpus ID

85025714433 (Scopus)

Source API URL

https://api.elsevier.com/content/abstract/scopus_id/85025714433

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