Abstract

Tuberculosis, caused by the organism Mycobacterium tuberculosis, is one of the major public health threats in the world. The emergence of multidrug resistant strains poses serious threats to the control of this disease due to the complex nature of second-line drug treatment. Upon infection, the bacterium goes through an initial replication phase after which it enters a nonreplicative, drug-resistant state of dormancy. The bacterium is able to survive in this dormant state for decades until the hosts immune system is weakened when it reactivates and causes the infectious disease.

Document Type

Patent

Patent Number

US 7,601,357

Application Serial Number

11/561,460

Issue Date

10-13-2009

Current Assignee

UCFRF

Assignee at Issuance

UCFRF

College

Burnett School of Biomedical Sciences

Department

Biomolecular Science Center

Allowance Date

6-5-2009

Filing Date

11-20-2006

Assignee at Filing

UCFRF

Filing Type

Nonprovisional Application Record

Donated

no

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