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Abstract

The year is 1853; the month July. Imagine that you are a 30-year old bank clerk from New York who has traveled to New Orleans to visit your younger sister, recently married to an assistant editor of the Picayune. Six days after your return to your native city, you suddenly develop chills and fever. Your head aches and you feel weak and nauseated. You collapse on the guest-room bed but, instead of experiencing relief from lying down, the muscles of your neck, back and legs start to ache severely and, over the next two days, you become so irritable and restless that you can only sleep in fits and starts.

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