Title

Prevalence and patient characteristics associated with CIN 3 in adolescents

Authors

Authors

A. E. Clements; C. A. Raker; A. S. Cooper;L. A. Boardman

Comments

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Abbreviated Journal Title

Am. J. Obstet. Gynecol.

Keywords

adolescent; cervical intraepithelial neoplasia 3; CERVICAL INTRAEPITHELIAL NEOPLASIA; HUMAN-PAPILLOMAVIRUS INFECTION; 2006; CONSENSUS GUIDELINES; YOUNG-WOMEN; CANCER; MANAGEMENT; OUTCOMES; FEMALES; LESIONS; RISKS; Obstetrics & Gynecology

Abstract

OBJECTIVE: We sought to identify patient characteristics associated with cervical intraepithelial neoplasia (CIN) 3 in adolescents. STUDY DESIGN: A cross-sectional cohort study was done using a colposcopic database. Data collected included demographic and clinical information as well as cytologic and histologic results. Variables associated with CIN 3 in the univariable analysis (P <=.10) were included in a multivariable logistic regression model. RESULTS: Of 614 adolescents evaluated, 48 (8%; 95% confidence interval, 6-10%) had CIN 3. No cancers were detected. In the univariable analysis, parity, >= 4 lifetime male sexual partners, and a history of sexually transmitted infections were associated with an increased risk of CIN 3. In the final model, only >= 4 sexual partners (compared to <4; adjusted odds ratio, 3.66; 95% confidence interval, 1.26-10.61) was significantly associated with the finding of CIN 3. CONCLUSION: CIN 3 was infrequently encountered in adolescents, and those with multiple sexual partners were at increased risk for CIN 3.

Journal Title

American Journal of Obstetrics and Gynecology

Volume

204

Issue/Number

2

Publication Date

1-1-2011

Document Type

Article; Proceedings Paper

Language

English

First Page

7

WOS Identifier

WOS:000286874900014

ISSN

0002-9378

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