Prevalence and patient characteristics associated with CIN 3 in adolescents

    Authors

    A. E. Clements; C. A. Raker; A. S. Cooper;L. A. Boardman

    Comments

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    Abbreviated Journal Title

    Am. J. Obstet. Gynecol.

    Keywords

    adolescent; cervical intraepithelial neoplasia 3; CERVICAL INTRAEPITHELIAL NEOPLASIA; HUMAN-PAPILLOMAVIRUS INFECTION; 2006; CONSENSUS GUIDELINES; YOUNG-WOMEN; CANCER; MANAGEMENT; OUTCOMES; FEMALES; LESIONS; RISKS; Obstetrics & Gynecology

    Abstract

    OBJECTIVE: We sought to identify patient characteristics associated with cervical intraepithelial neoplasia (CIN) 3 in adolescents. STUDY DESIGN: A cross-sectional cohort study was done using a colposcopic database. Data collected included demographic and clinical information as well as cytologic and histologic results. Variables associated with CIN 3 in the univariable analysis (P < =.10) were included in a multivariable logistic regression model. RESULTS: Of 614 adolescents evaluated, 48 (8%; 95% confidence interval, 6-10%) had CIN 3. No cancers were detected. In the univariable analysis, parity, > = 4 lifetime male sexual partners, and a history of sexually transmitted infections were associated with an increased risk of CIN 3. In the final model, only > = 4 sexual partners (compared to < 4; adjusted odds ratio, 3.66; 95% confidence interval, 1.26-10.61) was significantly associated with the finding of CIN 3. CONCLUSION: CIN 3 was infrequently encountered in adolescents, and those with multiple sexual partners were at increased risk for CIN 3.

    Journal Title

    American Journal of Obstetrics and Gynecology

    Volume

    204

    Issue/Number

    2

    Publication Date

    1-1-2011

    Document Type

    Article; Proceedings Paper

    Language

    English

    First Page

    7

    WOS Identifier

    WOS:000286874900014

    ISSN

    0002-9378

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