Keywords

type 2 diabetes; type 2 diabetes mellitus; cognitive impairments; cognitive decline; HbA1c; blood glucose control

Abstract

Type 2 diabetes mellitus (T2DM), presents a significant health burden globally, affecting millions of individuals, especially in the elderly population. While its association with cardiovascular diseases and cognitive impairments is well-documented, further research on the precise influence of glucose control on cognitive outcomes in elderly T2DM patients is necessary. This scoping review aims to address this gap by investigating the impact of HbA1c levels representing glycemic control on the risk of developing cognitive impairments in elderly patients with T2DM. A literature search was conducted on MEDLINE and eligible studies involved T2DM patients aged 60 or older, with documented cognitive function and glycemic status. Screening and selection processes were conducted following PRISMA guidelines, and three relevant articles were selected for review. Most of the findings suggest a possible association between higher HbA1c levels and cognitive decline. Such results provide valuable insights regarding medical approaches focusing on glucose control that could be created to prevent and delay cognitive decline in T2DM patients.

Thesis Completion Year

2024

Thesis Completion Semester

Spring

Thesis Chair

Linda Papa

College

College of Sciences

Thesis Discipline

Neuroscience

Language

English

Access Status

Open Access

Length of Campus Access

None

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Rights Statement

In Copyright