Title

Tissue Distribution Of Isocitrate Dehydrogenase In Drosophila-Melanogaster

Comments

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Keywords

Biochemistry & Molecular Biology; Entomology

Abstract

Distribution of the soluble form of isocitrate dehydrogenase (ICDH) in imaginal discs, some larval and some adult Drosophila melanogaster structures was determined. ICDH distribution in imaginal discs provides an opportunity to study in morphologically similar cells the degree of biochemical differentiation, the ontogeny of ICDH pattern formation, tissue determination at the disc level and in some instances the position of developmental compartments. Differential activity for ICDH was observed in the eye-antennal disc, dorsal prothoracic disc, all leg discs, wing and haltere discs, genital disc, larval gut, plus the adult ovaries and the male genital structures. Uniform activity was found in the labial disc, larval salivary gland cells, nests of abdominal histoblasts and in larval fat bodies. No detectable ICDH activity was observed in the imaginal cells of the clypeus-labrum, the imaginal cells of the foregut, the imaginal ring of the hindgut, or in clusters of imaginal cells of ICDH negative regions of the midgut. It is concluded that ICDH, like aldehyde oxidase, is non-random in its tissue distribution and does provide an additional internal histochemical marker for developmental studies.

Journal Title

Insect Biochemistry

Volume

11

Issue/Number

3

Publication Date

1-1-1980

Document Type

Article

Language

English

First Page

277

WOS Identifier

WOS:A1981LV07100005

ISSN

0020-1790

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