Title

The Preparation Of Aromatic Amidino Esters And Their Reaction With Primary Amines

Comments

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Abbreviated Journal Title

Tetrahedron

Keywords

Chemistry; Organic

Abstract

A series of aromatic amidino esters were prepared from the respective anthranilic acids by reaction with DMF acetal. These amidino esters were then condensed with a variety of primary amines to give the corresponding 3-substituted quinazolin-4-ones. Based on substituent effects, and the application of acid catalysis, a unifying mechanism is proposed.

Journal Title

Tetrahedron

Volume

43

Issue/Number

8

Publication Date

1-1-1987

Document Type

Article

Language

English

First Page

1747

Last Page

1752

WOS Identifier

WOS:A1987H235600001

ISSN

0040-4020

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