Title

An improved synthesis of O-benzoyl protected hydroxamates

Authors

Authors

Q. X. H. Wang; J. King;O. Phanstiel

Comments

Authors: contact us about adding a copy of your work at STARS@ucf.edu

Abbreviated Journal Title

J. Org. Chem.

Keywords

BIOLOGICAL PROPERTIES; BIOSYNTHESIS; SIDEROPHORE; NANNOCHELIN; INHIBITORS; Chemistry, Organic

Abstract

Several primary amines (R-NH2) were converted to their corresponding O-benzoyl protected hydroxamates under biphasic conditions. The intermediate (benzoyloxy)amines (R-NHOCOPh) were generated using benzoyl peroxide dissolved in CH2Cl2 and an aqueous carbonate buffer (pH 10.5) at room temperature. Subsequent acylation with R'COCl gave the protected hydroxamates (R'CONROCOPh) in good overall yields (56-89%).

Journal Title

Journal of Organic Chemistry

Volume

62

Issue/Number

23

Publication Date

1-1-1997

Document Type

Article

DOI Link

http://dx.doi.org/10.1021/jo971126q

Language

English

First Page

8104

Last Page

8108

WOS Identifier

WOS:A1997YG45200036

ISSN

0022-3263

Recommended Citation

"An improved synthesis of O-benzoyl protected hydroxamates" (1997). Faculty Bibliography 1990s. 2128.
https://stars.library.ucf.edu/facultybib1990/2128