Abbreviated Journal Title
Antimicrob. Agents Chemother.
Keywords
Ribonucleotide Reductase Inhibitor; Didox; Microbiology; Pharmacology & Pharmacy
Abstract
Several known mammalian ribonucleotide reductase inhibitors featuring a polyhydroxyphenyl and/or hydroxamate moiety as the active group were screened for potency in inhibiting growth of the malaria parasite Plasmodium falciparum. Compounds containing a 2,3- or 3,4-dihydroxyphenyl group as well as benzohydroxamate appear to be the most effective inhibitors of the malaria parasite.
Journal Title
Antimicrobial Agents and Chemotherapy
Volume
42
Issue/Number
9
Publication Date
1-1-1998
Document Type
Article
Language
English
First Page
2456
Last Page
2458
WOS Identifier
ISSN
0066-4804
Recommended Citation
Holland, Kevin P.; Elford, Howard L.; Bracchi, Valerie; Annis, Charles G.; Schuster, Sheldon M.; and Chakrabarti, Debopam, "Antimalarial activities of polyhydroxyphenyl and hydroxamic acid derivatives" (1998). Faculty Bibliography 1990s. 2282.
https://stars.library.ucf.edu/facultybib1990/2282
Comments
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