Authors

K. P. Holland; H. L. Elford; V. Bracchi; C. G. Annis; S. M. Schuster;D. Chakrabarti

Comments

Authors: contact us about adding a copy of your work at STARS@ucf.edu

Abbreviated Journal Title

Antimicrob. Agents Chemother.

Keywords

RIBONUCLEOTIDE REDUCTASE INHIBITOR; DIDOX; Microbiology; Pharmacology & Pharmacy

Abstract

Several known mammalian ribonucleotide reductase inhibitors featuring a polyhydroxyphenyl and/or hydroxamate moiety as the active group were screened for potency in inhibiting growth of the malaria parasite Plasmodium falciparum. Compounds containing a 2,3- or 3,4-dihydroxyphenyl group as well as benzohydroxamate appear to be the most effective inhibitors of the malaria parasite.

Journal Title

Antimicrobial Agents and Chemotherapy

Volume

42

Issue/Number

9

Publication Date

1-1-1998

Document Type

Article

Language

English

First Page

2456

Last Page

2458

WOS Identifier

WOS:000075737400059

ISSN

0066-4804

Share

COinS