Direct Imaging In A Water Layer Of Human-Chromosome Fibers Composed Of Nucleosomes And Their Higher-Order Structures By Laser-Plasma X-Ray Contact Microscopy
Abbreviated Journal Title
LASER-PLASMA X-RAYS; CONTACT MICROSCOPY; HYDRATED HUMAN CHROMOSOME; FIBER; UNFIXED; UNSTAINED; NUCLEOSOME; SUPERBEAD; ORGANIZATION; CHROMATIN; Microscopy
X-ray contact microscopy with a 300-ps-duration laser-plasma X-ray source has been used to image hydrated human chromosomes. Clearly imaged are individual nucleosomes and their higher-order particles (superbeads), elementary chromatin fibrils c. 30nm in diameter and their higher-order fibres of various sizes up to c. 120nm in diameter. The results demonstrate that X-ray microscopy is now capable of opening a new path of investigation into the detailed structures of hydrated chromosome fibres in their natural state.
Journal of Microscopy-Oxford
"Direct Imaging In A Water Layer Of Human-Chromosome Fibers Composed Of Nucleosomes And Their Higher-Order Structures By Laser-Plasma X-Ray Contact Microscopy" (1994). Faculty Bibliography 1990s. 2955.