The Application Of Vinylogous Iminium Salts And Related Synthons To The Regiocontrolled Preparation Of 2,3- And 2,5-Disubstituted Pyrroles

Authors

    Authors

    J. T. Gupton; S. A. Petrich; L. L. Smith; M. A. Bruce; P. Vu; K. X. Du; E. E. Dueno; C. R. Jones;J. A. Sikorski

    Comments

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    Abbreviated Journal Title

    Tetrahedron

    Keywords

    Chemistry, Organic

    Abstract

    The reaction of 1-substituted vinamidinium salts with sarcosine ethyl ester produced 2,3-disubstituted pyrroles; a similar reaction with glycine ethyl ester gave 2,5-disubstituted pyrroles. Reactions of related three-carbon synthons with sarcosine and glycine were studied under basic, neutral and acidic conditions which demonstrated the utility of these derivatives for the regiocontrolled preparation of disubstituted pyrroles. Copyright (C) 1996 Elsevier Science Ltd

    Journal Title

    Tetrahedron

    Volume

    52

    Issue/Number

    20

    Publication Date

    1-1-1996

    Document Type

    Article

    Language

    English

    First Page

    6879

    Last Page

    6892

    WOS Identifier

    WOS:A1996UK08900004

    ISSN

    0040-4020

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