Title

An Efficient, Regiocontrolled Synthesis Of 5-Aryl-2-Carbethoxypyrroles From 3-Aryl-3-Chloropropeniminium Salts

Authors

Authors

J. T. Gupton; D. A. Krolikowski; R. H. Yu; P. Vu; J. A. Sikorski; M. L. Dahl;C. R. Jones

Comments

Authors: contact us about adding a copy of your work at STARS@ucf.edu

Abbreviated Journal Title

J. Org. Chem.

Keywords

PYRROLE-2-CARBOXYLATES; 1, 3-DIKETONES; HETEROCYCLES; Chemistry, Organic

Abstract

A variety of 3-aryl-3-chloropropeniminium salts react with alpha-amino acid esters under basic conditions to produce 2-carbethoxy-5-arylpyrroles in a regioselective manner. The overall process represents a short, efficient, and convergent synthesis of 2,5-disubstituted pyrroles, and azomethine ylides or azapentadienyl anions may be involved as intermediates.

Journal Title

Journal of Organic Chemistry

Volume

57

Issue/Number

20

Publication Date

1-1-1992

Document Type

Article

DOI Link

http://dx.doi.org/10.1021/jo00046a033

Language

English

First Page

5480

Last Page

5483

WOS Identifier

WOS:A1992JQ22700033

ISSN

0022-3263

Recommended Citation

"An Efficient, Regiocontrolled Synthesis Of 5-Aryl-2-Carbethoxypyrroles From 3-Aryl-3-Chloropropeniminium Salts" (1992). Faculty Bibliography 1990s. 465.
https://stars.library.ucf.edu/facultybib1990/465