A meshless CFD approach for evolutionary shape optimization of bypass grafts anastomoses

    Authors

    Z. El Zahab; E. Divo;A. Kassab

    Comments

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    Abstract

    Improving the blood flow or hemodynamics in the synthetic bypass graft end-to-side distal anastomosis (ETSDA) is an important element for the long-term success of bypass surgeries. An ETSDA is the interconnection between the graft and the operated-on artery. The control of hemodynamic conditions through the ETSDA is mostly dictated by the shape of the ETSDA. Thus, a formal ETSDA shape optimization would serve the goal of improving the ETSDA flowfield. Computational fluid dynamics (CFD) is a convenient tool to quantify hemodynamic parameters; also, the genetic algorithm (GA) is an effective tool to identify the ETSDA optimal shape that modify those hemodynamic quantities such that the optimization objective is met. The present article introduces a unique approach where a meshless CFD solver is coupled to a GA for the purpose of optimizing the ETSDA shape. Three anastomotic models are optimized herein: the conventional ETSDA, the Miller cuff ETSDA and the hood ETSDA. Results demonstrate the effectiveness of the proposed integrated optimization approach in obtaining anastomoses optimal shapes.

    Journal Title

    Inverse Problems in Science and Engineering

    Volume

    17

    Issue/Number

    3

    Publication Date

    1-1-2009

    Document Type

    Article

    First Page

    411

    Last Page

    435

    WOS Identifier

    WOS:000264530700010

    ISSN

    1741-5977

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