The application of vinylogous iminium salt derivatives to the regiocontrolled preparation of heterocyclic appended pyrazoles

    Authors

    J. T. Gupton; S. C. Clough; R. B. Miller; B. K. Norwood; C. R. Hickenboth; I. B. Chertudi; S. R. Cutro; S. A. Petrich; F. A. Hicks; D. R. Wilkinson;J. A. Sikorski

    Abbreviated Journal Title

    Tetrahedron

    Keywords

    pyrazoles; vinamidinium salts; chloropropeniminium salts; chlorovinyl; aldehydes; REGIOSELECTIVE SYNTHESIS; INHIBITORS; Chemistry, Organic

    Abstract

    A variety of vinylogous iminium salt derivatives have been examined as useful precursors for the regiocontrolled synthesis of heterocyclic appended pyrazoles. The reaction conditions for such processes have been optimized and the regiochemical preferences have been determined. Such reaction sequences represent methodologies which may have useful applications for the preparation of biologically interesting substances. (C) 2002 Elsevier Science Ltd. All rights reserved.

    Journal Title

    Tetrahedron

    Volume

    58

    Issue/Number

    27

    Publication Date

    1-1-2002

    Document Type

    Article

    Language

    English

    First Page

    5467

    Last Page

    5474

    WOS Identifier

    WOS:000176653300009

    ISSN

    0040-4020

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