Title

The application of vinylogous iminium salt derivatives to the regiocontrolled preparation of heterocyclic appended pyrazoles

Authors

Authors

J. T. Gupton; S. C. Clough; R. B. Miller; B. K. Norwood; C. R. Hickenboth; I. B. Chertudi; S. R. Cutro; S. A. Petrich; F. A. Hicks; D. R. Wilkinson;J. A. Sikorski

Abbreviated Journal Title

Tetrahedron

Keywords

pyrazoles; vinamidinium salts; chloropropeniminium salts; chlorovinyl; aldehydes; REGIOSELECTIVE SYNTHESIS; INHIBITORS; Chemistry, Organic

Abstract

A variety of vinylogous iminium salt derivatives have been examined as useful precursors for the regiocontrolled synthesis of heterocyclic appended pyrazoles. The reaction conditions for such processes have been optimized and the regiochemical preferences have been determined. Such reaction sequences represent methodologies which may have useful applications for the preparation of biologically interesting substances. (C) 2002 Elsevier Science Ltd. All rights reserved.

Journal Title

Tetrahedron

Volume

58

Issue/Number

27

Publication Date

1-1-2002

Document Type

Article

Language

English

First Page

5467

Last Page

5474

WOS Identifier

WOS:000176653300009

ISSN

0040-4020

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